Education/Working Experience
Oct. 2012 --Now：Dalian Medical University, Institute of Cancer Stem Cell, Professor
Jul. 2004-Sep. 2012：Yangzhou University, College of Biological Science and Technology, Associate professor
Jun. 2001-Jun. 2004：H Lee Moffitt Cancer Center, University of South Florida, USA, Postdoctoral
Aug. 2000-May. 2001：Zhejiang University, Lecturer
Sep. 1997-Jul. 2000：Institute of Veterinary Research in Harbin, Chinese Academy of Agricultural Sciences, PhD
Sep. 1991-Jun. 1994：Yangzhou University, Master
Sep. 1984-Jun. 1989：Yangzhou University, Bachelor
Publication
1.Jiang K, Liu M, Lin G, Mao B, Cheng W, Liu H, Jozsef G, Zhu H, Yuan Z, Deng W, Liu Q, Gong P, Bi X, Meng S*. Tumor suppressor Spred2 interaction with LC3 promotes autophagosome maturation and induces autophagy-dependent cell death. Oncotarget. 2016 Mar 25. (*Corresponding author)
2. Li Z, Jiang K, Zhu X, Lin G, Song F, Zhao Y, Piao Y, Liu J, Cheng W, Bi X, Gong P, Song Z, Meng S*. Encorafenib (LGX818), a potent BRAF inhibitor, induces senescence accompanied by autophagy in BRAFV600E melanoma cells. Cancer Lett. 2016 Jan 28; 370(2): 332-44 .(*Corresponding author)
3. Lulu Hu, Sulan Sun, Tianpeng Wang, Yingchun Li, Ke Jiang, Guibin Lin, Yan Ma, Martin P. Barr, Fei Song, Guirong Zhang, Songshu Meng*. Oncolytic Newcastle Disease Virus triggers cell death of lung cancer spheroids and is enhanced by pharmacological inhibition of autophagy. American Journal Cancer Research. 2015;5(12): 3612-23(*Corresponding author)
4. Song Q, Mao B, Cheng J, Gao Y1, Jiang K, Chen J, Yuan Z, Meng S* . YAP enhances autophagic flux to promote breast cancer cell survival in response to nutrient deprivation. PLoS One. 2015 Mar 26; 10(3)(*Corresponding author)
5. Jiang K, Li Y, Zhu Q, Xu J, Wang Y, Deng W, Liu Q, Zhang G, Meng S* Pharmacological modulation of autophagy enhances Newcastle disease virus-mediated oncolysis in drug-resistant lung cancer cells. BMC Cancer. 2014 Jul 30;14:551.(*Corresponding author)
6. Qi Xie, Jing Chen, Han Feng, Shengyi Peng, Ursula Adams, Yujie Bai, Li Huang, Ji Li, Junjian Huang, Songshu Meng*, Zengqiang Yuan*. YAP/TEAD-mediated transcription regulates the cellular senescence. Cancer research, 2013 Jun 15;73(12):3615-24. (*Corresponding author)
7. Songshu Meng*, Jiansheng Xu, Yantao Wu, Chan Ding*. Targeting autophagy to enhance oncolytic virus-based cancer therapy. Expert Opin Biol Therapy. 2013 Jun;13(6):863-73.(*Corresponding author)
8. Songshu Meng*, Zhizhi Zhou, Fei Chen, Xiangang Kong, Huairan Liu, Ke Jiang, Wenbo Liu, Maozhi Hu, Xiaorong Zhang, Chan Ding* , Yantao Wu*. Newcastle disease virus induces apoptosis in cisplatin-resistant human lung adenocarcinoma A549 cells in vitro and in vivo. Cancer Lett. 317(1):56-64，2012.(*Corresponding author)
Research Projects/Grants
1: National Natural Science Foundation of China: Oncolytic Newcastle disease virus kills drug-resistant lung cancer cells via autophagy effect: mechanism and application. (2014.1-2017.12)
2: National Natural Science Foundation of China: Tumor suppressor SASH1-mediated regulation of the Hippo/YAP pathway in breast cancer tumorigenesis (2016.1----2019.12)
3. Qizhen Project of Dalian Medical University: 2013-2018
Admission Plan/Requirements
1 Person, Speaking English
