About IEC

Songshu Meng

Title: Professor
Email: ssmeng@dmu.edu.cn
Major: Cell Biology

                   Education/Working Experience
Oct. 2012 --Now:Dalian Medical University, Institute of Cancer Stem Cell, Professor
Jul. 2004-Sep. 2012:Yangzhou University, College of Biological Science and Technology, Associate professor
Jun. 2001-Jun. 2004:H Lee Moffitt Cancer Center, University of South Florida, USA, Postdoctoral
Aug. 2000-May. 2001:Zhejiang University, Lecturer
Sep. 1997-Jul. 2000:Institute of Veterinary Research in Harbin, Chinese Academy of Agricultural Sciences, PhD
Sep. 1991-Jun. 1994:Yangzhou University, Master
Sep. 1984-Jun. 1989:Yangzhou University, Bachelor
1.Jiang K, Liu M, Lin G, Mao B, Cheng W, Liu H, Jozsef G, Zhu H, Yuan Z, Deng W, Liu Q, Gong P, Bi X, Meng S*. Tumor suppressor Spred2 interaction with LC3 promotes autophagosome maturation and induces autophagy-dependent cell death. Oncotarget.  2016 Mar 25. (*Corresponding author) 
2. Li Z, Jiang K, Zhu X, Lin G, Song F, Zhao Y, Piao Y, Liu J, Cheng W, Bi X, Gong P, Song Z, Meng S*. Encorafenib (LGX818), a potent BRAF inhibitor, induces senescence accompanied by autophagy in BRAFV600E melanoma cells. Cancer Lett. 2016 Jan 28; 370(2): 332-44 .(*Corresponding author) 
3. Lulu Hu, Sulan Sun, Tianpeng Wang, Yingchun Li, Ke Jiang, Guibin Lin, Yan Ma, Martin P. Barr, Fei Song, Guirong Zhang, Songshu Meng*. Oncolytic Newcastle Disease Virus triggers cell death of lung cancer spheroids and is enhanced by pharmacological inhibition of autophagy. American Journal Cancer Research. 2015;5(12): 3612-23(*Corresponding author) 
4. Song Q, Mao B, Cheng J, Gao Y1, Jiang K, Chen J, Yuan Z, Meng S* . YAP enhances autophagic flux to promote breast cancer cell survival in response to nutrient deprivation. PLoS One. 2015 Mar 26; 10(3)(*Corresponding author)
5. Jiang K, Li Y, Zhu Q, Xu J, Wang Y, Deng W, Liu Q, Zhang G, Meng S* Pharmacological modulation of autophagy enhances Newcastle disease virus-mediated oncolysis in drug-resistant lung cancer cells. BMC Cancer. 2014 Jul 30;14:551.(*Corresponding author) 
6. Qi Xie, Jing Chen, Han Feng,  Shengyi Peng, Ursula Adams, Yujie Bai, Li Huang, Ji Li, Junjian Huang, Songshu Meng*, Zengqiang Yuan*. YAP/TEAD-mediated transcription regulates the cellular senescence. Cancer research, 2013 Jun 15;73(12):3615-24. (*Corresponding author) 
7. Songshu Meng*, Jiansheng Xu, Yantao Wu, Chan Ding*. Targeting autophagy to enhance oncolytic virus-based cancer therapy. Expert Opin Biol Therapy. 2013 Jun;13(6):863-73.(*Corresponding author) 
8. Songshu Meng*, Zhizhi Zhou, Fei Chen, Xiangang Kong, Huairan Liu, Ke Jiang, Wenbo Liu, Maozhi Hu, Xiaorong Zhang, Chan Ding* , Yantao Wu*. Newcastle disease virus induces apoptosis in cisplatin-resistant human lung adenocarcinoma A549 cells in vitro and in vivo. Cancer Lett. 317(1):56-64,2012.(*Corresponding author)
Research Projects/Grants
1: National Natural Science Foundation of China: Oncolytic Newcastle disease virus kills drug-resistant lung cancer cells via autophagy effect: mechanism and application. (2014.1-2017.12)
2: National Natural Science Foundation of China: Tumor suppressor SASH1-mediated regulation of the Hippo/YAP pathway in breast cancer tumorigenesis (2016.1----2019.12)
3. Qizhen Project of Dalian Medical University: 2013-2018
Admission Plan/Requirements 
1 Person, Speaking English