Education/Professional Experience
Sep.1980-Jul.1986 Norman Bethune Medical University English class of Clinical medine, bachelordegree
Sep.1986-Jul.1989 Norman Bethune Medical University Oncology, Masterdegree
Sep.2001-Jul.2004 Dalian Medical University Molecular biology, Ph.D.
Sep.1989.7up to now The First Affiliated Hospital of Dalian Medical University Department of Oncology,Professor andDepartment Director
Jun.1998-Dec.1998 Japan KitakyushuMedical Center Cancer center, Visiting scholar
Oct.2006-Mar.2007 Northwestern University, USA Robert Lurrie cancer center, Visiting scholar
Participation in the Academic Community
Standing Committee member of the Chinese society of Clinical Oncology (CSCO)
Committeemember of Chemotherapy, Chinese Anti-cancer Association
Vice Chairman of Small cell lung cancer expert committee-CSCO
Vice Chairman of Cancer Society of Liaoning Province, Chinese Medical Association
Vice Chairman of ChemotherapyCommittee,Liaoning Anti-cancer Association
Committeemember of Oncologist, Chinese Medical Doctor Association
Publication
1. Ginsenoside Rg3 inhibits melanoma cell proliferation through down-regulation of histone deacetylase 3 (HDAC3) and increase of p53 acetylation. PLOS ONE, 2014, 9 (12): e115401. IF:3.534, Corresponding author
doi: 10.1371/journal.pone.0115401.
2. Ginsenoside Rg3-induced EGFR/MAPK pathway deactivation inhibits melanoma cells proliferation via decreasing of FUT4/LeY expression. Int J Oncol. 2015, 46 (4): 1667-76. IF:3.025, Corresponding author; doi: 10.3892/ijo.2015.2886.
3. Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death. Int J Oncol. 2015, 47: 701-709. IF: 3.025, Corresponding author; doi: 10.3892/ijo.2015.3057.
4. Clinical observation of liver cancer patients treated with axitinib and cabozantinib after failed sorafenib treatment: a case report and literature review.Cancer Biol Ther. 2015; 16 (2): 215-8. IF: 3.072, Corresponding author; doi: 10.4161/15384047.2014.962318.
5. Ginsenoside Rg3 inhibits epithelial-mesenchymal transition (EMT) and invasion of lung cancer by down-regulating FUT4. Oncotarget ,2016, 7(2):1619-1632.IF:6.359 ,Corresponding author;DOI:10.18632/oncotarget.6451
6. Ginsenoside Rg3 induces FUT4-mediated apoptosis in H. pylori CagA-treated gastric cancer cells by regulating SP1 and HSF1 expressions. Toxicol In Vitro, 2016 ,31:158-166. IF:2.903, Co-corresponding author;DOI:10.1016/j.tiv.2015.09.025
7. Effects of cinobufacini injection on cell proliferation and the expression of topoisomerases in human HepG-2 hepatocellular carcinoma cells, 2015, MOLECULAR MEDICINE REPORTS, Volume: 12; Issue: 1; Pages: 1598-1604; Impact Factor(JCR2014) IF: 1.554, Co-corresponding author; DOI:10.3892/mmr.2015.3552
Research Projects/Grants
Principal Investigator of the National Natural Science Foundation of China-“Study on the mechanism of Rg3 on the effect of novel serum marker d-GM3 in the malignant melanoma metastasis”
Admission Plan/Requirements
One for Doctoral Candidate
One for Master’s Degree Candidate