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Biochemistry and Molecule Biology

Jianhui Fan

Date:2017/10/27Clicks:

Education/Working Experience

Education Experience

2009.9-2012.12  Dalian Medical University  

Major: Biochemistry and Molecular Biology

Research: Function of glycans in tumor cells.

Degree: Ph.D.

2003.9-2006.06  Dalian Medical University  

Major: Biochemistry and Molecular Biology

Research: Function of ribonuclease inhibitor in tumor cells.

Degree: Master

1998.9-2003.06  Chengde Medical University

Major: Clinical Medicine

Degree: Bachelor 

Working Experience

2006.7-      Biochemistry and Molecular Biology Department of Dalian Medical University

Research area:Tumor Biology

Structure and functions of human ribonuclease inhibitor in tumor cells.

The effects of glucosaminyltransferase on tumor cell metastasis

 

Participation in the Academic Community

Member of Chinese society of Biochemistry and molecular biology (CSBMB)

Vice Chairman of Education and Training Youth Committee, CSBMB

 

Publication

1. Tang Y, Liu P, Tian Y, Xu Y, Ren F, Cui X, Fan J*. Overexpression of ribonuclease inhibitor defines good prognosis and suppresses proliferation and metastasis in human colorectal cancer cells via PI3K/AKT pathway. Clin Transl Oncol. 2015, 17(4):306-313. (corresponding author)
2. Arshad Ahmed Padhiar, Jianhui Fan, Ying Tang, Juanhan Yu, Shujing Wang, Linhua Liu, Bachir Niang, Max Efui Annani-Akollor, Lifen Wang, Qi Wang, Jianing Zhang. Upregulated β1-6 branch N-glycan marks early gliomagenesis but exhibited biphasic expression in the progression of astrocytic glioma. Am J Cancer Res.2015, 5(3):1101-1116.
3. FAN Jian-hui, HE Jing-na, WANG Shu-jing, ZHENG Wei-long, JIN Li-yuan, ZHANG Jia-ning*. Construction and application of lentiviral-based system against N-Acetylglucosaminyltransferase. Chinese Journal of Microecology, 2014, 26(5): 518-521.
4. ZHANG Hai-feng,WANG Zhu-xin,ZHANG Jie,LI Wei,FAN Jian-hui*.  The significance of VEGF expression in serum and cancer tissue in colon cancer patients. Chinese Journal of Microecology. 2014, 26(10): 1151-1154. (corresponding author)
5. Jianhui Fan, Ying Tang, Jingna He, Shujing Wang, Lifen Wang, Jianing Zhang*;Silencing of GnT-V Potentiates the Antitumor Activity of Gemcitabine against Bladder Cancer Cells. Glycoconj J. 2013, 30: 423
6. Fan Jianhui,Wang Shujing,Yu Shengjin,He Jingna,Zheng Weilong,Zhang Jianing*. Effects of down-regulation of lentivirus-mediated GnTⅣa on the proliferation and invasion of mouse hepatoma Hca-F cells. Chin J Cancer Biother, 2013, 20(6): 673-678.
7. Fan J., Wang S., Yu S., He J., Zheng W., Zhang J.*. N-acetylglucosaminyltransferase IVa regulates metastatic potential of mouse hepatocarcinoma cells through glycosylation of CD147. Glycoconj J. 2012, 29(5-6), 323-334.
8. J. Fan, J. He, S. Wang, Y. Guo, Y. Dang, S. Yu, J. Zhang*. Expression of N-actylglucosaminyltransferase IVa Regulates Invasion of Mouse Hepatocarcinoma Cells in vitro. Glycoconj J. 2011, 28: 263.

 

Research Projects/Grants

1. The role of N-acetylglucosaminyltransferase IV in synthesis of N-glycan branches and in lymph node metastasis potential in mouse hepatocarcinoma cells. 2010.1-2012.12 (the third participant) National Natural Science Foundation of China (NSFC NO. 30970648)
2. The  effects of GnT-Ⅴ expression and N-glycosylation of transporter on the chemosensitivity in bladder cancer. 2015.01-2017.12 (in charge) National Natural Science Foundation of China (NSFC NO. 31400687)

 

Admission Plan/Requirements

 

Admission Plan: Master degree student, 1-2 /Year

Requirements:

1. The student should be non-Chinese citizens with a valid passport, should be between 20-35 years old, healthy, and has obtained bachelor degree with good marks.

2. He/her native language is English or the official language is English.


         

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