Education/Working Experience

201402—Present China  Dalian Medical University            Professor

201105—201402 USA   Johns Hopkins University       Postdoctoral  Research

Scientist / Teaching assistant

200806—201105 USA National Center for Toxicological Research  Postdoctoral fellow

200207—200407 China  CapitalBio Corporation            Research Scientist

200107—200207 China  YiShengTang Biology Medicine Ltd  Research Scientist

200409 — 200807 China  Institute of Biophysics, Chinese Academy of Sciences Biochemistry and Molecular Biology   Ph.D.

199809 — 200107 China  Fu Dan University     Microbiology       M.S.

199409 — 199807 China  Wu Han University     Microbiology       B.S.

Participation in the Academic Community

Psychoneuroimmunology Research Society 2013.11— Present  

Environmental Mutagen Society  2011.01—  Present  Member

Member The Society of Toxicology  2009.09—Present  Member

Publication

1. Zhiguang Li, Hongzheng Dai,  Suzanne N. Martos,  Beisi Xu, Yang Gao, Teng Li, Guangjing Zhu, Dustin E. Schones, and Zhibin Wang. Distinct roles of DNMT1-dependent and -independent methylation patterns in the genome of mouse embryonic stem cells. Genome Biology. 2015 Jun 2;16:115.(IF=10.81) 

2. Li Zhiguang, Qin T, Wang K, Hackenberg M, Yan J, Gao Y, Yu L, Shi L, Su Z, Chen T: Integrated microRNA, mRNA, and protein expression profiling reveals microRNA regulatory networks in rat kidney treated with a carcinogenic dose of Aristolochic Acid. BMC genomics 2015, 16(1):1-11 (IF=4.041)

3. Wang Y, Li Zhiguang, Chen T, Zhao X: Understanding the aristolochic acid toxicities in rat kidneys with regulatory networks. IET Systems Biology 2015, 9(4):141-146 Accepted. (IF=1.672)

4. Meng F, Li Zhiguang, Yan J, Manjanatha M, Shelton S, Yarborough S, Chen T: Tissue-specific microRNA responses in rats treated with mutagenic and carcinogenic doses of aristolochic acid. Mutagenesis 2014, 29(5):357-65. (IF=3.497)

5. Chen Z, Barbi J, Bu S, Yang HY, Li Z, Gao Y, Jinasena D, Fu J, Lin F, Chen C, Zhang J, Yu N, Li X, Shan Z, Nie J, Gao Z, Tian H, Li Y, Yao Z, Zheng Y, Park BV, Pan Z, Zhang J, Dang E, Li Zhiguang, Wang H, Luo W, Li L, Semenza GL, Zheng SG, Loser K, Tsun A, Greene MI, Pardoll DM, Pan F, Li B: The ubiquitin ligase stub1 negatively modulates regulatory T cell suppressive activity by promoting degradation of the transcription factor foxp3. Immunity 2013, 39(2):272-285. (IF=19.748)

6. Meng F, Hackenberg M, Li Zhiguang, Yan J, Chen T: Discovery of novel microRNAs in rat kidney using next generation sequencing and microarray validation. PloS one 2012, 7(3):e34394. (IF=3.73)

7. Chen T, Li Zhiguang, Yan J, Yang X, Salminen W: MicroRNA expression profiles distinguish the carcinogenic effects of riddelliine in rat liver. Mutagenesis 2012, 27(1):59-66. (IF=3.5)

Research Projects/Grants

Liao Ning Pan Deng Scholar Fund(2014-2016)

NSFC General Projects: Mechanism Investigation of the establishment of aberrant methylation at tumor suppressor gene promoters via DNMT1 and polII.(2014-2018)

Admission Plan/Requirements

The applicant should be between 23-35 years old, healthy, has obtained bachelor degree with good scores(GPA>3.75), has working experience, has solid financial support to afford the study and living expenses in China.

Requires students to have good biological statistics or bioinformatics background.

This major can accept one student.