Education/Working Experience

2013 - Present  Prof. College of Basic Medical Sciences, Dalian medical University.

2007 - 2012 Prof. College of Bioengineering, Dalian University, China

2003 - 2007 Postdoctoral fellowship, Department of Glycotherapeutics, Graduate School of Medicine, Osaka University, Japan. Field: Glycobiology

1999 - 2003 Ph.D. Student, in Laboratory of Immunology, Osaka Prefecture University, Japan. Field: Mucosal Immunization.

1997 - 1999 Student, in Laboratory of Immunology, Osaka Prefecture University, Japan.

1996 - 1997   Research Associate. Department of Immunology & Microbiology, Yanbian University, China.

1993 - 1996 Master course Student, in Laboratory of Immunology, Department of Veterinary Science, Yanbian University, China.

1989 - 1993 Bachelor course student, in Department of Veterinary Science, Yanbian University, China. Field: Veterinary Medicine

Participation in the Academic Community

2012-2016 Member of the Chinese Society for Immunology

2006-2016 Member of the Japanese Society for Immunology

2006-2016 Member of the Japanese Society for Glycobiology

Publication

1.  Xue K, Song J, Yang Y, Li Z, Wu C, Jin J, W. Li *. PAX5 promotes pre-B cell proliferation by regulating the expression of pre-B cell receptor and its downstream signaling. Mol Immunol. 2016 Mar 23;73:1-9.

2.  W. Li *, R. Yu, B. Ma, Y. Yang, X. Jiao, Y. Liu, H. Cao, W. Dong, L. Liu, K. Ma, T. Fukuda, Q. Liu, T. Ma, Z. Wang, J. Gu, J. Zhang and N. Taniguchi. Core fucosylation of IgG-BCR is required for antigen recognition and antibody production. Journal of Immunology. 2015, Mar 15;194(6):2596-606.

3.  W. Li, D. Wang, Y. Chi, R. Wang, F. Zhang, G. Ma, Z. Chen, J. Li, Z. Liu, E. Matsuura and Q. Liu. 7-ketocholesteryl-9-carboxynonanoate enhances the expression of ATP binding cassette transporter A1 via CD36. Atherosclerosis, 2013, 226(1), 102-109.

4.   Y. Pang, Y. Zhang, H. Wang, J. Jin, J. Piao, J. Piao, Q. Liu, W. Li *. Reduction of Salmonella enteritidis number after infections by immunization of liposomes-associated recombinant SefA. Avian Disease 2013;57(3):627-33.

5.  W. Li *, Q. Liu, Y. Pang, J. Jin, H. Wang, H. Cao, Z. Li, X. Wang, B. Ma, Y. Chi, R. Wang, A. Kondo, J. Gu, and N. Taniguchi. Core fucosylation of mu heavy chains regulates the assembly of precursor B cell receptors and its intracellular signaling. Journal of Biological Chemistry 2012, 287(4): 2500-2508.

6.  Y. Zhang *, W. Li * et al. Recombinant domain V of β2-glycoprotein I inhibits the formation of a 7-ketocholesteryl-9-carboxynonanoate and β2-glycoprotein I complex. Journal of Biochemisty 2011 Jan;149(1):35-42.

7.  Y. Pang, H. Wang, Z. Li, J. Piao, J. Piao, Y. Chi, J. Jin, Q. Liu, W. Li *. Immune response to liposomes associated recombinant SEF21 following oral immunization in chickens. Avian Disease 2012 Jun; 56(2): 347-353.

8.  Z. Huang *, W. Li * et al. 7-ketocholesteryl-9-carboxynonanoate induced nuclear factor-kappa B activation in J774A.1 macrophages. Life Science 2010, 87(19-22): 651-657.

9.  W. Li et al. Reduced {alpha}4{beta}1 integrin /VCAM-1 Interactions Lead to Impaired Pre-B Cell Repopulation in Alpha 1,6-Fucosyltransferase Deficient Mice. Glycobiology. 2008, 18(1): 114-124.

10. W. Li et al. Down regulation of trypsinogen expression is associated with growth retardation in alpha 1,6-fucosyltransferase-deficient mice: attenuation of proteinase-activated receptor 2 activity. Glycobiology. 2006, 16(10): 1007-1019.

Research Projects/Grants

1. Regualtion of core fucosyltransferase on the CD4+ T cell activation and proliferation. National Natural Science Foundation of China (NSFC)-31570797, 2016.1-2019.12, 780,000RMB.

2. The mechanism of core fucosylation in mature B cell recognition of Ag, activation and Ab production. National Natural Science Foundation of China (NSFC)-31270864, 2013.1-2016.12, 800,000RMB.

3. Roles of Fut8 in pre-B cell proliferation and differentiation. National Natural Science Foundation of China (NSFC)-30972675. 2010.1-2012.12, 320,000RMB.

Admission Plan/Requirements

One graduated student / year

The student should have a good English writing ability and some research experience.