About IEC

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Zhaoyang Xiao

Title: Professor
Email: xiaozhaoy2012@163. com
Major: EICU

Education/Working Experience

2007.10-2010.10 Department of Pharmacology, Physiology &Therapeutics, University of North Dakota,postdoc

(博士后美国北达克他大学药理学,生理学,治疗学系)

Participation in the Academic Community

2008, 2010 Membership of America Neuroscience Association (美国神经科学协会会员)

Research Direction

Mechanism of neuroprotection, general anesthesia, sepsis (神经保护,全麻及浓毒症机制)

Thesis or Articles Published

1.     Zhang HP,Xiao Z, Cilz NI, Hu B, Dong H, Lei S. Bombesin facilitates GABAergic transmission and depresses epileptiform activity in the entorhinal cortex. Hippocampus. 2014, 24(1):21-31. ( Impact factor=5.492 )                                                      共同第一作者

2.     Xiao Z, Jaiswal MK, Deng PY, Matsui T, Shin HS, Porter JE, Lei S.Requirement of phospholipase C and protein kinase C in cholecystokinin-mediated facilitation of NMDA channel function and anxiety-like behavior.Hippocampus. 2012, 22(6):1438-50.( Impact factor=5.492)                                                                                       第一作者

3.     Hu S, Wang W, Wang C, Ma R,*Xiao Z, Dong H. Langerhans cells histiocytosis presenting as multisystem disorder in an infant: a case report. International Journal of Dermatology. 2012;51:709-712 ( Impact factor=1.342 )                                                                通讯作者

4.     Xiao Z, Deng PY, Rojanathammanee L, Yang C, Grisanti L, Permpoonputtana K, Weinshenker D, Doze VA, Porter JE, Lei S. Noradrenergic depression of neuronal excitability in the entorhinal cortex by activation of TREK-2 K+channels. Journal of Biological Chemistry.2009, 284(16):10980-10990. (Impact factor=5.328)          第一作者

5.     Xiao Z, Deng PY, Yang C, Lei S. Modulation of GABAergic transmission by muscarinic receptors in the entorhinal cortex of juvenile rats.Journal of Neurophysiology. 2009,102 (2): 659-69. (Impact factor=3.483)                                                                                 第一作者

6.     Deng PY,Xiao Z, Yang C, Rojanathammanee L, Grisanti L, Watt J, Geiger JD, Liu R, Porter JE, Lei S. Activation of GABABreceptors inhibits neuronal excitability and spatial learning in rat entorhinal cortex by activating TREK-2 K+channels. Neuron. 2009, 63(2):230-43.(Impact factor=13.41)

7.     Deng PY,Xiao Z, Jha A, Ramonet D, Matsui T, Leitges M, Shin HS, Porter JE, Geiger JD, Lei S. Cholecystokinin Facilitates Glutamate Release by Increasing the Number of Readily Releasable Vesicles and Releasing Probability.Journal of Neuroscience. 2010, 30(15):5136-48. (Impact factor=7.745)    

8.     Deng PY,Xiao Z,Lei,S. Distinct Modes of Modulation of GABAergic Transmission by Group I Metabotropic Glutamate Receptors in Rat Entorhinal Cortex.Hippocampus. 2010, 20(8):980-93. (Impact factor=4.609)

9.     Dahaba AA, Yin J,Xiao Z, Su J, Bornemann H, Dong HL, Xiong L. Different propofol/remifentanil or sevoflurane/remifentanil Bispectral Index levels for electrocorticographic spike identification during epilepsy surgery.Anesthesiology. 2013, 119(3):582-92.

10. Wang S, Kurada L, Cilz NI, Chen XT,Xiao Z, Dong HL, Lei S. Adenosinergic Depression of Glutamatergic Transmission in the Entorhinal Cortex of Juvenile Rats via Reduction of Glutamate Release Probability and the Number of Releasable Vesicles.PLOS ONE. 2013 2013, 8(4):e62185.

11. Dahaba AA, SULJEVIĆ I, Oettl K,Xiao Z, Su J, Dong HL, Xiong L, Reibnegger G. Influence of acute normovolemic hemodilution on the pharmacokinetics of cisatracurium besylate.Minerva anestesiologica. 2013 , 79(11):1238-47.

12. Dahaba AA, Perelman SI, Moskowitz DM, Bennett HL, Shander A,Xiao Z, et al. Geographic regional differences in rocuronium bromide dose-response relation and time course of action: an overlooked factor in determining recommended dosage. Anesthesiology. 2006, 104(5): 950-3. (Impact factor=4.05)

Scientific Research Project


1.      Ongoing Grant Support

1)     Optimal depth of anesthesia with propofol or sevoflrane for electrocorticographic (ECoG) spike identification during epilepsy surgery.ASIA PACIFIC ANAESTHESIA INNOVATOR AWARDS (PI: Zhaoyang Xiao)

(Total direct cost: $ 10,000)             2012                                             

2.      Grant Support

1)      The roles of activation of two pores domain potassium channel TREK-2 by adenosine on epileptogensis. National Natural Science Foundation of China. Grant No: 81071052 (PI: Zhaoyang Xiao)

(Total direct cost: RMB300, 000)   2011-2013                                        


1.       癫痫发生与发展中“双孔钾通道TREK-2腺苷开放途径”研究. 2010获国家自然科学基金面上项目30万(第一申请人,基金号:81071052 /2011.1- 2013.12)

2.       2011亚太麻醉创新者基金1万美元(第一申请人)