About IEC

Yingjie Wu

Title: Professor
Email: yingjiewu@dmu.edu.cn
Major: Cell Biology

Education/Working Experience  

Working Experience

2013.01 - Present, Professor, Institute of Genome Engineered Animal Models for Human Disease, Dalian Medical University

2012.09 - Present, Professor, part-time, Basic Science & Craniofacial Biology, College of Dentistry, New York University

2011.09 - Present, Associate Professor, part-time, Endocrinology, Diabetes and Bone Disease Icahn, Mount Sinai School of Medicine

2005.09 - 2011.08, Associate Professor, Endocrinology, Diabetes and Bone Disease Icahn, Mount Sinai School of Medicine

2002.02 - 2005.03, senior fellow, National Heart, Lung, and Blood Institute, NIH

1999.01 - 2002.02, research assistant, Department of Biology, University of Pennsylvania

1989.07 - 1992.02, Instructor, Liaoning Normal University


Education Experience

1995.12 - 1998.12, Postdoctoral research, University of Pennsylvania;

1992.02 - 1995.07, Ph.D. study, Biochemistry and Molecular Biology, China Agricultural University

1986.09 - 1989.07, M.S. study, Biochemistry and Molecular Biology, Shenyang Agricultural University,

1982.09 - 1986.07, Bachelor study, Biology, Northeast Normal University


Participation in the Academic Community  

1.Evaluation expert of National Great Talent Project "Innovative talent promotion plans" leading talent and innovation team

2.Evaluation expert of International Science & Technology Cooperation Program of China Member of the American Endocrine Society

3.Member of the international IGF Research Institute

4.Member of the American Society for Bone and Mineral Research Member of Sino-American Biotechnology and Pharmaceutical Professionals Association

5.Member of the International Chinese Musculoskeletal Research Society



Total IF55

1.Yingjie Wu, Chengyu Liu, Hui Sun, Archana Vijayakumar, Pejman Raeisi Giglou, Joshua Oppenheimer, Shoshana Yakar and Derek LeRoith. Growth hormone receptor regulates β cell hyperplasia and glucose-stimulated insulin secretion in obese mice. The Journal of Clinical Investigation 2011; May 9, 121(6):2422–2426.  SCI: 16.915

2. Archana Vijayakumar*, Yingjie Wu*, Chengyu Liu, Hui Sun, Shoshana Yakar and Derek LeRoith, Targeted loss of GHR signaling in mouse skeletal muscle protects from high-fat diet-induced metabolic deterioration, Diabetes 2012 Jan;61(1):94-103. (*Co-first authors).

SCI: 8.889

3. Yingjie Wu, Pnina Brodt, Hui Sun, Wilson Mejia, Ruslan Novosyadlyy, Nomeli Nunez, Xiaoli Chen, Arnulfo Mendoza, Sung-Hyeok Hong, Chand Khanna and Shoshana Yakar. Insulin-like growth factor-I regulates the liver microenvironment in obese mice and promotes liver metastasis. Cancer Research. 2010 Jan 1;70(1):57-67. SCI: 8.438


Research Projects/Grants  

1.National Natural Science Foundation of China, The Mechnism of Tissue Specific Gene Knockout of GHR in β Cell Function, Project Number 81471000, funding amount 780,000 RMB, 2015.01-2018.12, project leader

2.International Science & Technology Cooperation Program of China: Establishing Gene Engineering Animal Models for Human Diseases with Highly Effective Gene Targeting Strategy, Project Number 2014DFA32120, funding amount 4,560,000 RMB, 2014.04-2017.03, project leader

3.Liaoning S&T Project: The Research and Development of Gene Engineering Animal New Strains and Gene Engineering Animal Models for Human Diseases, Project Number 201402893, funding amount 200,000 RMB, 2014.04-2017.03, project leader

4.Liaoning Provincial Natural Science Foundation of talent’s cultivate project: The establishment of CRISPR/Cas9 efficient targeted gene modification system to study diabetes-related genes function, Project Number 2014023042, funding amount 50,000 RMB,  2014.07-2016.06, project leader

5.Doctoral Program of Higher Specialized Research Fund Project, Study on Dendrobium’s ZiYin effect and mechanism by using IGF1R gene mutations in type 2 diabetic mice, Project Number 20132105110002, funding amount 120,000 RMB, 2014.01-2016.12, project leader

6.Ministry of Human Resources and Social Security of the People's Republic of China 2013 Students studying science and technology activities preferred funded projects, funding amount 80,000 RMB, project leader

7.2013 Dalian The fourth hi-chance project: Use of plant bioreactor to produce long-acting insulin, Project Number 22012100106, funding amount 1,000,000 RMB, 2013.12 -2016.12, project leader

8.International Science & Technology Cooperation Program of China: Using molecular agricultural product pharmaceutical proteins and biological active substances, Project Number 2012DFA30450, funding amount 4,400,000 RMB, 2012.05-2015.04, US official (Chinese partner Shandong Province High-Tech Research Center)

9.International Science & Technology Cooperation Program of China: Joint R & D of absorbable internal fixation devices and bone tissue engineering scaffold, Project Number 2010DFB50890, funding amount 14,340,000 RMB, 2010.01-2011.12, US official (Chinese partner Application of CAS Changchun Chemical)
10.NIH/DDHS:IGF and IGF Receptor Function in Mammary Development,Project Number 5R01DK060612-09,2007.09-2013.07,Co-Investigator (5% of effort co-Investigator)

11.Application Form for High-end Foreign Experts Recruitment Program: The use of new technology to build efficient gene targeting major diseases in animal models of human development platform, Project Number GDT20152100020, 290,000 RMB, 2015.01-2015.12, project leader

12.Liaoning S&T Project: The Research and Development of Gene Engineering Animal New Strains and Gene Engineering Animal Models for Human Diseases (Carry-over projects), Project Number 2015408003, funding amount 200,000 RMB, 2015.01-2017.12, project leader


Admission Plan/Requirements  

Recruit one Master student every year;

Preference will be given to candidates who have medical background.