Education/Working Experience
Education experience :
1.2002/7–2006/6，Dalian Medical University， Biochemistry and Molecular Biology，Doctor，Mentor：Zhang Jianing
2.1991/9–1994/6，Dalian Medical University， Biochemistry，Master，Mentor：Zhang Yaozheng
3.1982/9–1986/6， Inner Mongolia Medical College，Pharmacy，Bachelor，Mentor：Luo Xing wu
Scientific research and Academic experience：
1.2002/6-to this day，Dalian Medical University ，Clinical Laboratory Department，Professor
2.1997/6-2002/6，Dalian Medical University ，Clinical Laboratory Department，Vice-Professor
3.1995/6-1997/6，Dalian Medical University ，Clinical Laboratory Department， Lecturer
4.1986/6-1991/9，Inner Mongolia Medical College， School of Basic Medical Sciences，Assistant
5.2007/7-2011/6，The Academy of Mititary Medical Sciences.，postdoctor:
Co-Advisor：He Chu fu
Participation in the Academic Community
Director of Biochemistry and Molecular Biologyin Liaoning province;
Director of Biochemistry and Molecular Biology in Dalian.
Publication
1. Zuo Y, Ren S, Wang M, Liu B, YangJ, Kuai X, Lin C, Zhao D, Tang L, He F. Novel roles of liver sinusoidalendothelial cell lectin in colon carcinoma cell adhesion, migration and in-vivometastasis to the liver. Gut. 2012;13(4) (IF 13.319)(the first author).
2.Chen C, Wang B, Sun J, Na H, Chen Z, Zhu Z, Yan L, Ren, S, Zuo Y. DAC can restore expression of NALP1 tosuppress tumor growth in colon cancer.CELLDEATH& DISEASE,2015 ; 6 (IF 5.177)（corresponding author）.
3. DC-SIGN, DC-SIGNR and LSECtin: C-Type Lectins for Infection.International Reviews of Immunology, 2014;33:54-66 (IF 5.280)（corresponding author）.
4. Jiang Y, ZhangC, Chen K, Chen Z, Sun Z, Zhang Z, Ding D, Ren S, Zuo Y. The clinicalsignificance of DC-SIGN and DC-SIGNR, which are novel markers expressed inhuman colon cancer. PLoS ONE 2014;12 (IF:3.543)（corresponding author）.
5. Chen Z, Jin H, HouY,Wang B, Chen C, Yang Z, Ding D, Zuo Y, Ren S.Activated P2X7 receptor upregulatesthe expression levels of NALP3 in P388D1 murine macrophage‑like cells.Mol Med Rep. 2015 Feb;11(2):1542-6（corresponding author）.
6．Ren S,ZhangY,WangY,LuiY,WeiW,HuangX,MaoW,ZuoY.Targeting P2X7 receptor inhibits themetastatic capability of murine lymphoid neoplasm cell P388D1 to lymph nodes.Cell Biology International. 2010;34(12):1205-11. (IF 1.747)（corresponding author）.
7．Lin C,RenS,ZhangL,JinH,SunJ,ZuoY.Extracellular ATP inducesCD44 shedding from macrophage-like P388D1 cell via P2X7 receptor. HematologicalOncology, 2011;16 Jun. (IF 2.475)（corresponding author）.
8．Zhang Y,Zhang J,Lin C,Wei W,Ren S,ZuoY. Overexpression of ASC in P388D1 murinelymphoma cells affects metastatic properties. Hematological Oncology, 2011;16Jun. (IF 2.475)（corresponding author）.
9．Lin C,ZuoY,Ren S. Small DuodenalGastrointestinal Stromal Tumor Presenting with Acute Bleeding Misdiagnosed asHemobilia: Two Case Reports.Oncology Letters. 2012; June 1: 1069-1071 (IF 0.2)（corresponding author）.
10．Zhang S,BaiJ,RenS,WangR,ZhangL,ZuoY.Sodium butyrate restoresASC expression and induces apoptosis in LS174T cells.Int J Mol Med.2012 (IF 1.5)（corresponding author）.
11．Zhuqing Zhang, Kai Chen, Longchao Yan, Ziyi Yang, ZhanmengZhu,Chunlin Chen, Jia Zeng, Wei Wei, Xia Qi, ShuangyiRen,YunfeiZuo. Low expression of DC-SIGNR in Non-Hodgkinlymphoma and significant correlations with LDH and β2-microglobulin.Biochemistry and Cell Biology,2013 Aug;91(4):214-20. (IF 2.6)（corresponding author）.
12. Yan Qin, YunjunGuo, Wei Wei, Bo Wang, HongfeiJin, Jianguo Sun, Xia Qia, Shuangyi Ren, and YunfeiZuo. Anti-tumor effect of β-elemenein murine hepatocellular carcinoma cell line H22 depends on the level of c-Metdown regulation. Biomedicine and Preventive Nutrition. 2012; 2:91-98,(corresponding author).
13. Yunlong Ding, Weibo Xuan, Chunlin Chen, ZheChen,Ziyi Yang, Yunfei ZUO, and Shuangyi Ren. Differences in carcinoembryonicantigen levels between colon and rectal cancer. Molecular and ClinicalOncology. 2014; 2:618-622,(corresponding author).
14. Shuai Zhang, Yijun Chen, Zhanmeng Zhu, YunlongDing, Shuangyi Ren and YunfeiZuo. Differential expression of carbohydrate antigen19‑9 in human colorectal cancer: A comparisonwith colon and rectal cancers. Molecular and Clinical Oncology.2103;1:1072-1078,(corresponding author).
Research Projects/Grants
1. NSFC, LSECtin effects on hepatic metastasis in gastric carcinoma ability and its mechanism 2015-2019,8 million,Leader.
2. NSFC,P2X7R participate in lymphoma lymph metastasispotency and its mechanism（30870550）, 2009-2011,3.3million,Leader.
3.NSFC,C-type lectin LSECtin in lymphoma lymphatic channel transfer function and its mechanism（31270867）,2012year,1.5million,Leader.
4.China postdoctoral foundation funding（The First Place)）,The role of LSECtin in colon cancer liver metastasis（20080440229），2008-2010，5 thousand,Leader.
5.Innovation team project in liaoning province department of education,The study of P2X7R and L-selectin in lymphoma by the lymphatic metastasis（2008T034）,2008-2010,1million,Leader.
Admission Plan/Requirements
Admission Plan:
1. Every year a Dr.
Requirements:
1.Only the PhD students every year.
