Education/Working Experience
1996-2001 Dalian Medical University Bachelor
2001-2004 Dalian Medical University Master
2004-2007 Chinese Academy of medical Sciences & Peking Union Medical College Ph.D
2007-2011 University of North Carolina, US Postdoc
2011-2013 University of North Carolina, US Research Assistant Professor
2013- Dalian Medical University Professor
Publication
1.Yang Wang*,Zefeng Wang,Efficient backsplicing produces translatable circular mRNAs.,RNA,2015,21(2):172-179. (SCI, IF=4.622)
2.Yang Wang*,Dan Chen,Haili Qian,Yihsuan Tsai,Shujuan Shao,Quentin Liu,Daniel Dominguez,Zefeng Wang(*),The Splicing Factor RBM4 Controls Apoptosis, Proliferation, and Migration to Suppress Tumor Progression.,Cancer Cell,2014,26(3):374-389.(SCI, IF=23.893)
3. Yang Wang* and Zefeng Wang*. Systematical identification of splicing regulatory cis-elements and cognate trans-factors. Methods. 2013 (In Press) (SCI, IF=4.5) (* Correspondence author)
4. Yang Wang, Zefeng Wang and Traci Hall. Engineered proteins with PUF scaffold to manipulate RNA metabolism. FEBS Journal. 2013 280 (16):3755-67.( SCI,IF=3.8)(Invited review, Cover article)
5. Yang Wang, Xinshu Xiao, et. al. A Complex Network of Factors with Overlapping Affinities Control Splicing Repression by Intronic Elements. Nature Structural Molecular Biology. 2013 Jan; 20(1):36-45 (SCI, IF=13.69)
6. Yang Wang, Meng Ma, Xinshu Xiao, et.al. Intronic Splicing Enhancers, Cognate Splicing Factors and Context Dependent Regulation Rules. Nature Structural Molecular Biology. 2012 Oct; 19(10):1044-52 (SCI, IF=13.69)
Research Projects/Grants
1. National Natural Science Foundation--Outstanding Youth Foundation, 2015-2017
2. The mechanism of RNA splicing regulation by splicing factor RBM4 and its role in tumorigenesis”, General Program of the National Natural Science Foundation of China, 2015-2018
3. “Mechanistic study of the reduction of RBM4 in cancer and its role in regulating the oncogenic SRSF1”, Newton Advanced Fellowship, 2015-2018
4. “The mechanistic study of the biogenesis and regulation of circular RNA using mini-gene reporter system”, Training Program of the Major Research Plan of the National Natural Science Foundation of China, 2016-2018
Admission Plan/Requirements
One Ph.D. student per year.
Candidates should be fluent in English, preferably with good bench skills.