About IEC

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Hongli Lin

Title: Chief Physian
Email: linhongli@vip.163.com
Major: Nephrology

    Education/Working Experience


    1998.9-2001.6      The Military Academy of the People's Liberation Army,

    BeiJing, China,

    Ph.D., Nephrology  

    1990.9-1993.9   China Medical University, LiaoNing Province, China,

    M.S., Medicine

    1985.9-1990.6      China Medical University, LiaoNing Province, China,

    M.D., Clinical Medicine


    2003.6- present     Renal Division, the First Affiliated Hospital of Dalian Medical

    University; LiaoNing Province, China;Professor, Chief physician

    2001.6- present     Renal Division, the First Affiliated Hospital of Dalian Medical

    University; LiaoNing Province, China; Director

    2000.6- 2003.06     Renal Division, the First Affiliated Hospital of Dalian Medical

    University; LiaoNing Province, China; associate professor,  associate Chief physician, Master Supervisor  

    1995.9- 2000.6     Renal Division, the First Affiliated Hospital of Dalian Medical

    University; LiaoNing Province, China; attending doctor

    1993.9-1995.6     Renal Division, the First Affiliated Hospital of Dalian Medical

    University; LiaoNing Province, China; physician


    Participation in the Academic Community

    2015-present      Director of the Key Lab of Liaoning Integrated control for chronic

     kidney diseases

    Director of Nephrology Society of Liaoning Medical Association

    Standing committee of Renal Pharmacological specific committee

    of Chinese Pharmacological Society

    2013-present      Director of the Center for Renal Translational Medicine of

     Liaoning Province.

    2012-present      Standing committee of Chinese Nephrologist Association

                    Associate director of the Nephrology and Purification Branch of

     China Medical Women’s Association

                    Standing committee and Deputy Secretary-General of Chinese

     Society of Nephrology

    2007-2012       Standing committee of Chinese Society of Blood Purification

     Administration of Chinese Hospital Association

    2011            Director of the Institution of Kidney Disease of Dalian Medical




    A. Refereed Original Articles in Journals (Corresponding author &First author) 

    1. Nan Shen, Hongli Lin, Taihua Wu, Dapeng Wang, Weidong Wang, Hua Xie, Jianing Zhang,  Zhe Feng. Inhibition of TGF-beta1-receptor posttranslational core fucosylation attenuates rat renal interstitial fibrosis. Kidney Int, 2013, 84(1),64-77. Corresponding author [IF:8.52]

    2. Zhou M, Ma H, Lin H, Qin J. Induction of epithelial-to-mesenchymal transition in proximal tubular epithelial cells on microfluidic devices. Biomaterials, 2014;35(5):1390-401. Corresponding author [IF:8.312]

    3. Lin H, Chen X, Wang J, Yu Z.Inhibition of apoptosis in rat mesangial cells by tissue inhibitor of metalloproteinase-1.Kidney Int. 2002 Jul;62(1):60-69. First author [IF:5.016]

    4. Lingyu Wang, Tuaner Zhang, Ming Fang, Nan Shen, Dapeng Wang, Jiaqi Teng, Hongli Lin. Podocytes protect glomerular endothelial cells from hypoxic injury via deSUMOylation of HIF-1alpha signaling. Int J Biochem Cell Biol.2014 Nov 3;58C:17-27. Corresponding author [IF:4.24]

    5. Lin H, Wang D, Wu T, Dong C, Shen N, Sun Y, Sun Y, Xie H, Wang N, Shan L. Blocking core fucosylation of TGF-β1 receptors downregulates their functions and attenuates the epithelial-mesenchymal transition of renal tubular cells. Am J Physiol Renal Physiol. 2011;300(4):F1017-25. First author [IF:3.682]

    6. Nan Wang, Yeqing Shao, Yan Mei, Li Zhang, Qinggang Li, Diangeng Li, Suozhu Shi, Quan Hong, Hongli Lin, Xiangmen Chen. Novel mechanism for mesenchymal stem cells in attenuating peritoneal adhesion: Accumulation in the lung and secreting TNFα-stimulating gene-6.Stem Cell Res Ther.2012, 3(6), 51. Corresponding author [IF:3.652]

    7. Cai X, Sheng J, Tang C, Nandakumar V, Ye H, Ji H, Tang H, Qin Y, Guan H, Lou F, Zhang D, Sun H, Dong H, Zhang G, Liu Z, Dong Z, Guo B, Yan H, Yan C, Wang L, Su Z, Li Y, Jones L, Huang XF, Chen SY, Wu T, Lin H. Frequent mutations in EGFR, KRAS and TP53 genes in human lung cancer tumors detected by ion torrent DNA sequencing.PLoS One. 2014;9(4):e95228. doi: 10.137Corresponding author [IF:3.534]

    8. Zhang J, Lin H, Yu C, Peng H, Bai R. Multiple autoimmune syndrome revealed by nephrogenic diabetes insipidus and hypokalaemic paralysis. Lupus 2013, 2, 1178–1181. Corresponding author [IF:2.481] 

    9. Lingyu Wang, Jingwei Zhu, Ming Fang, Tuaner Zhang, Hua Xie, Nan Wang, Nan Shen, Hui Guo, Bo Fu, Hongli Lin. Inhibition of p53 deSUMOylation Exacerbates Puromycin Aminonucleoside-Induced Apoptosis in Podocytes. Int J Mol Sci. 2014, 15, 21314-21330. Corresponding author [IF: 2.339]

    10. Li N, Xie H, Li L, Wang J, Fang M, Yang N, Lin H. Effects of Honokiol on Sepsis-Induced Acute Kidney Injury in an Experimental Model of Sepsis in Rats. Inflammation, 2014; 37(4):1191-9. Corresponding author [IF:1.921]

    11. Liu YXie HLin HChen SWang WZhao GZhang X. Coexistence of Fabry Disease and Membranous Nephropathy. Iran J Kidney Dis. 2016 Jan; 10(1):48-50. Corresponding author [IF:0.98]

    12. Sun Yanling, Xie Hua, Lin Hongli. Construction and identification of recombinant adenovirus carrying human TIMP-1 shRNA gene. Genetics and Molecular Research, 2014 July 14. Corresponding author [IF:0.85]

    B. Refereed commentary Article in Journal

    Manjeri A. Venkatachalam, Joel M. Weinberg. New wrinkles in old receptors: core

     fucosylation is yet another target to inhibit TGF-β signaling. Kidney International

     (2013) 84, 11–14. (IF=8.52)


    Research Projects/Grants

    2016-2020  Key program of National Science Foundation of China; “The

     characteristic changes and the action mechanisms of core fucosylation in renal

     interstitial fibrosis”. The Director.

    2015-2018  Nonprofit Industry Research Project of National Health and Family

     Planning Commission “The establishment of evaluation and specification of

     key technology of blood purification for affecting the quality of life in uremic

     patients and medical expenses”. The Director.

    2013-2016  The Research Fund for the Doctoral Program of Higher Education

    “The effect of core fucosylation on biological behavior of kidney pericyte by

    hypoxia-reoxygenation injury”

     “Outstanding academic leaders support plan”; the First Affiliated Hospital of

    Dalian Medical University

    Admission Plan/Requirements

    1 to 2 PhD and post-doctoral students per year.